Identifying EOR-1 Binding Sites and Chromatin Accessibility in Relation to NHR-25 in C. elegans
Summer 2025 - PresentUndergraduate Researcher, Davidson College · Prof. Deborah Thurtle-Schmidt
Investigating the role of EOR-1 as a pioneer factor in regulating NHR-25 binding and chromatin accessibility in C. elegans.
Optimized ATAC-seq and CUT&RUN protocols for increasing data quality with higher cell viability after homogenization.
Built custom bioinformatics pipelines in Python and R for processing and analyzing sequencing data, including differential accessibility and peak calling analyses.
Methods
- ATAC-seq
- CUT&RUN
- Python, Bash & R
- Diffential analysis & peak calling
- Poster presentations at Davidson College Fall Research Symposium and ABRCMS 2025