Research

Selected research projects spanning genomics, epigenetics and biochemistry.

Identifying EOR-1 Binding Sites and Chromatin Accessibility in Relation to NHR-25 in C. elegans

Summer 2025 - Present

Undergraduate Researcher, Davidson College · Prof. Deborah Thurtle-Schmidt

Investigating the role of EOR-1 as a pioneer factor in regulating NHR-25 binding and chromatin accessibility in C. elegans.

Optimized ATAC-seq and CUT&RUN protocols for increasing data quality with higher cell viability after homogenization.

Built custom bioinformatics pipelines in Python and R for processing and analyzing sequencing data, including differential accessibility and peak calling analyses.

Methods

  • ATAC-seq
  • CUT&RUN
  • Python, Bash & R
  • Diffential analysis & peak calling
  • Poster presentations at Davidson College Fall Research Symposium and ABRCMS 2025

Fibrillation Kinetics of Human Lysozyme under Crowding Conditions

Spring 2025

Undergraduate Researcher, Davidson College · Prof. Jeffrey Myers

Studied amyloid fibrillation behavior of human lysozyme under saccharide and synthetic crowding agents using fluorescence-based kinetic assays.

Compared aggregation dynamics across lysozyme variants to assess sequence-dependent effects.

Methods

  • Fluorescence spectroscopy
  • Sigmoidal regression analysis
  • BLAST sequence analysis
  • Poster presentations at Davidson College Verna Case Symposium, Spring 2025

Localization and Function of Transcription Factor Sm49580 in Schistosoma mansoni

Summer 2024

Visiting Undergraduate Researcher, Fudan University · Dr. Jipeng Wang

Investigated the localization and functional role of transcription factor Sm49580 in the tegument of S. mansoni through RNAi and in situ hybridization.

Combined molecular assays with in vivo infection models to examine phenotypic consequences of gene knockdown.

Methods

  • RNA interference (RNAi)
  • Molecular cloning
  • WISH & FISH
  • Mouse husbandry

Lab Memories!

Winning the Summer Research Trivia

Winning the Summer Research Trivia with the DTS Lab, Summer 2025!

At ABRCMS 2025 Conference

DTS Lab at ABRCMS 2025 in San Antonio, TX! (ft. Dr. Wessner)